Fertility runs on metabolism. We measure it, then rebuild it.
A doctor-led 90-day program. Along with your resting metabolism, we measure 9 core biometrics under the pillars of your health, for both of you, her and him. A personalized plan rebuilds them together, and a retest proves the change before your next cycle.
For couples in IVF, trying naturally, or told "unexplained."
The variable your clinic isn't measuring.
Your labs were normal. Your body wasn't lying. You've taken the supplements, tracked the cycle, done everything that was asked. And still, one variable went unmeasured: the metabolic environment an egg, and an embryo, actually has to grow in.
Metabolism quietly shapes egg quality, sperm quality, hormones and energy, and standard fertility labs never test it. We do. Then we rebuild it with a plan made for your body, not a protocol made for everyone.
Sources: O'Hearn et al., Journal of the American College of Cardiology (2022) · Heller & Clermont (1963) · Gougeon, Human Reproduction (1986)
Conception is built, not wished for.
Eggs and sperm remodel on a roughly ninety-day cycle. The program is built to match it, exactly.
Breath analysis, at home
A medical-grade resting test on your own couch: seated, mask on, about ten minutes. No treadmill, no needles. The same class of device used in elite performance labs.
9 core biometrics, decoded
Resting oxygen use, CO₂ production, respiratory exchange ratio, heart rate, heart-rate variability, ventilation, breathing frequency, tidal volume and mechanical efficiency. The clearest picture of your resting metabolism you've ever had, explained by your care team, from the framework Dr. Mari built.
A plan that flows with your cycle
Personalized nutrition, training, recovery and supplements, built around your data and adjusted weekly with your metabolic coach. Never a protocol made for everyone. His plan runs on the same clock: sperm rebuilds across roughly the same ninety days hers does.
Proof you can hold
Twelve weeks later we measure again, in the exact window in which eggs and sperm remodel, and show you, number by number, what changed.
The before, the after, and exactly what moved.
A readout you can hold, not take on faith.
Every engagement starts and ends with hard data on a medical-grade device, not one or two numbers inferred from a wrist. You see the before, the after, and exactly what changed.
Illustrative readout for staging, not a real client result.
The gold standard, from your couch.
Our method is indirect calorimetry: the recognized gold standard for measuring resting metabolism and energy use, recommended by clinical nutrition societies including ESPEN, ASPEN and SCCM, and relied on by hospitals and elite performance labs (Priem et al., Sensors, 2023). Resting metabolism commonly accounts for 60 to 75 percent of your daily energy burn.
Your Oura, Whoop or Lumen estimates. This measures at the source, then measures again at 90 days to prove the change.
Research links metabolic factors like insulin resistance to fertility on both sides (Reproductive BioMedicine Online, 2017; Frontiers in Endocrinology, 2024). The test reads the resting metabolism your plan rebuilds, for her and for him.
Half of fertility is his. Almost no one builds for him.
Roughly half of fertility challenges involve male factor, yet nearly every program is built only for her. Sperm remodels on the same ninety-day cycle as eggs, so we treat his metabolism as an equal project: his own baseline, his own plan, his own retest. The levers are real: in a randomized trial, men who lost weight through diet raised sperm count and concentration, and kept the gains (Andersen et al., Human Reproduction, 2022).
Conception is a team sport. We build for the team.
IVF doesn't ask about your metabolism. We do.
We sit beside your reproductive endocrinologist, your genetic counselor and your protocol, optimizing the one variable they don't measure. Never against your clinic. Always beside it.
Two of you. Two plans. One 90-day window.
Solo or together, every path starts and ends on the device: a baseline, a personalized plan, and a retest at 90 days.
Her plan or his: one baseline, one personalized 90-day remodel, one retest, with weekly check-ins from your care team.
Both of you: two baselines, two synchronized plans across one 90-day metabolic cycle, two retests. Sperm and egg quality treated as equal projects.
We'll walk through both programs on your consultation: what each includes, and which fits where you are.
The layer IVF doesn't cover.
IVF is the most powerful clinical tool in fertility, and nothing here replaces it. Its job is the embryo, the protocol and the transfer. Ours is the metabolic environment both of you bring to it. Never against your clinic, always beside it.
For her
In a study of overweight women who weren't ovulating, a six-month diet-and-exercise program restored ovulation in roughly 90% of participants (Clark et al., Human Reproduction, 1995). ASRM supports weight management for natural conception in that group (2021), and research shows even 5 to 10 percent weight loss can restart ovulation (van Oers et al., 2016).
For IVF
Research shows Mediterranean-style eating in the months before IVF is associated with higher live birth rates in women under 35 (Karayiannis et al., Human Reproduction, 2018), with couple-level findings pointing the same direction (Vujkovic et al., Fertility and Sterility, 2010).
For him
In a randomized trial, men who lost weight through diet raised sperm count and concentration and kept the gains (Andersen et al., Human Reproduction, 2022). Moderate exercise is associated with better sperm parameters, while excess can work against them (Fertility and Sterility, 2024), a case for a plan built to him.
Unexplained doesn't mean unexplainable. It means no one measured the right thing.
Insulin resistance appears in unexplained infertility more often than expected, in both sexes (Reproductive BioMedicine Online, 2017; Frontiers in Endocrinology, 2024).
A physician-scientist in your corner.
Dr. Mari Mitrani, MD, PhD
Physician-Scientist
Designed the scientific foundation the platform is built on. She built a fertility genetics laboratory before this program existed. Not a coach with a certificate, a physician-scientist whose research is the reason the science holds up.
Your care team
Metabolic coach · Specialists as needed
A dedicated metabolic coach runs your testing and your weekly check-ins, with specialists joining as your plan calls for it. Every plan runs on the framework Dr. Mari built, and every readout is measured against it, at baseline and at 90 days.
You were never the problem. You were the unmeasured variable.
We don't promise a baby. We promise the clearest picture of your fertility you've ever had, a plan built on it, and a care team that picks up the phone. Whatever you choose next, another transfer, a first try, a pause, you do it with data you didn't have before.
The work doesn't end at a positive test. For clients who conceive, we stay on as your metabolic partner through pregnancy and into the first year, remeasuring as your body changes with every trimester.
Questions, answered.
Is this instead of IVF? +
When should I start? +
What does the visit look like? +
Is my partner included? +
Do you guarantee a pregnancy? +
What does it cost? +
Who actually works with me? +
How is this different from my Oura or Whoop? +
I have PMOS (formerly PCOS). Is this for me? +
Is this really for my partner too? +
Stop optimizing in the dark.
Hope is not a protocol. Measurement is. Book a consultation with our care team. We'll review where you are, what we'd measure, and whether this is the right fit.
Book a consultation →