The Science | The Vital Insight Fertility
The science

The variable your clinic isn't measuring.

Metabolism shapes egg quality, sperm quality, hormones and energy. Standard fertility labs never test it. We do — on a medical-grade device, at baseline and at 90 days.

The method

Indirect calorimetry. The gold standard.

Indirect calorimetry is the recognized gold standard for measuring resting metabolism and energy use, recommended by clinical nutrition societies including ESPEN, ASPEN and SCCM, and relied on by hospitals and elite performance labs (Priem et al., Sensors, 2023).

Resting metabolism commonly accounts for 60 to 75 percent of your daily energy burn. Your Oura, Whoop or Lumen estimate. Indirect calorimetry measures — at the source, then again at 90 days to prove the change.

What we measure

23 biomarkers under the pillars of your resting metabolism.

Not one or two numbers inferred from a wrist. A full read of how your body uses oxygen, produces energy, regulates stress, and moves air — the substrate every cell in your reproductive system runs on.

Energy production

Metabolic rate & fat oxidation

Resting metabolic rate. Respiratory exchange ratio. Mitochondrial function. Fat-burning efficiency. The engine your reproductive system runs on.

Nervous system

HRV & autonomic balance

Heart-rate variability. Sympathetic/parasympathetic activation. Recovery capacity. The stress signal that quietly regulates ovulation and sperm production.

Oxygen & airflow

Lung utilization & ventilation

Ventilation efficiency. Breathing frequency. Tidal volume. Mechanical efficiency. How well you're actually delivering oxygen where it needs to go.

The link to fertility

Why this matters on both sides.

Research links metabolic factors like insulin resistance to fertility outcomes in both sexes (Reproductive BioMedicine Online, 2017; Frontiers in Endocrinology, 2024). Insulin resistance appears in unexplained infertility more often than expected.

For her. In a study of overweight women who weren't ovulating, a six-month diet-and-exercise program restored ovulation in roughly 90% of participants (Clark et al., Human Reproduction, 1995). ASRM supports weight management for natural conception in that group (2021).

For IVF. Mediterranean-style eating in the months before IVF is associated with higher live birth rates in women under 35 (Karayiannis et al., Human Reproduction, 2018), with couple-level findings pointing the same direction (Vujkovic et al., Fertility and Sterility, 2010).

For him. In a randomized trial, men who lost weight through diet raised sperm count and concentration and kept the gains (Andersen et al., Human Reproduction, 2022).

The 90-day window is not arbitrary.

Eggs and sperm remodel on a roughly ninety-day cycle (Gougeon, Human Reproduction, 1986; Heller & Clermont, 1963). That's why the program measures at day zero, remodels for twelve weeks, and retests at day ninety — exactly the window in which the biology can actually change.

See how the 90-day program is structured  →

Technology Validated & Trusted By

Stop optimizing in the dark.

Book a consultation with our care team. We'll review where you are, what we'd measure, and whether this is the right fit.

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